LUCEY-DRISCOLL SYNDROME. Other entities represented in this entry: BREAST MILK JAUNDICE, INCLUDED. Phenotype-Gene Relationships. Location. Lucey–Driscoll syndrome is an autosomal recessive metabolic disorder affecting enzymes involved in bilirubin metabolism. It is one of several disorders. Lucey-Driscoll syndrome. Prevalence: ; Inheritance: ; Age of onset: Neonatal; ICD P; OMIM: ; UMLS: C; MeSH: ; GARD:
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Retrieved from ” https: Rare; 24 cases reported. Gilbert’s syndrome Crigler—Najjar syndrome Lucey—Driscoll syndrome. Health care resources for this disease Expert centres 69 Diagnostic tests 7 Patient organisations 22 Orphan drug s 0. Usually all siblings are affected.
OMIM Entry – # – HYPERBILIRUBINEMIA, TRANSIENT FAMILIAL NEONATAL; HBLRTFN
Displaying of 3 results. The cause of transient neonatal hyperbilirubinemia may be steroidal substances in the plasma and milk of the mother that inhibit conjugation of bilirubin Lucey et al. The presence of significant neonatal jaundice frequently associated with a familial pattern.
Bruno Bissonnette, et al.
Sign in via OpenAthens. Cause The common cause is congenital, but it can also be caused by maternal steroids passed on through breast milk to the newborn. Pop-up div Successfully Displayed This div only appears when the trigger link is hovered over.
Lucey-driscoll Syndrome (disorder): Disease Bioinformatics: Novus Biologicals
Dubin—Johnson syndrome Rotor syndrome. You can also find results for a single author or contributor.
Unconjugated hyperbilirubinemia resulting in jaundice usually presenting on the third to fifth day of life and persisting for 3 weeks. In infants with uninterrupted breastfeeding, the hyperbilirubinemia disappeared slowly and driscill still be detected 12 driscolp after birth. Use this site remotely Bookmark your favorite content Track your self-assessment progress and more!
Drugs that interfere with metabolism of bilirubin or that may displace bilirubin from albumin could increase the risk of hyperbilirubinemia or kernicterus. Three of the 16 died of kernicterus, and one was left with quadriplegic cerebral palsy. Network Currently no links.
It is different from breast feeding-associated jaundice breast-fed infants have higher bilirubin levels than formula-fed ones. Rapid Recognition and Perioperative Implications.
Sulfonamides, ceftriaxone, pancuronium, and chloral hydrate are associated with hyperbilirubinemia. Another example is mental retardation in the offspring of women with phenylketonuria Mabry et al.
The hereditary hyperbilirubinemias include 1 those resulting in predominantly unconjugated hyperbilirubinemia, such as Gilbert or Arias syndrome, Crigler-Najjar syndrome type I, and Crigler-Najjar syndrome type II; and 2 those resulting in predominantly conjugated hyperbilirubinemia, such as Dubin-Johnson syndrome, Rotor syndrome, and other forms of intrahepatic cholestasis.
Transient familial neonatal hyperbilirubinemia. It is different from breast feeding-associated jaundice breast-fed infants have higher bilirubin levels than formula-fed ones.
Treatment – Lucey Driscoll syndrome Not supplied. Cases transmitted as an autosomal recessive trait gene map locus is 2q37 have been reported. Jaundice occurring in breast-fed neonate around the fourth to seventh day of life, persisting beyond physiologic jaundice, and with no other identifiable cause, probably resulting from a milk component that inhibits uridine diphosphoglucuronic acid UDPGA glucuronyl transferase, thus resulting in a prolonged unconjugated hyperbilirubinemia.
CC ]. Transient Familial Neonatal Hyperbilirubinemia. Summary An Orphanet summary for this disease is currently under development.