The ABCD2 score is a clinical prediction rule used to determine the risk for stroke in the days following a transient ischemic attack Its usefulness was questioned. The California, ABCD, and ABCD2 risk scores (ABCD system) were developed to help stratify short-term stroke risk in patients with TIA (transient ischemic. However, the ABCD2 and related scores have achieved particular prominence such that the ABCD2 score is recommended for use in UK stroke prevention.

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Two studies have bacd2 association [ 4344 ] of DWI abnormalities with increasing scores and two studies [ 1845 ] have found poor correlation between the scores and the presence of DWI abnormalities. To reduce the impact of any between-study heterogeneity, we considered separately shroke 10 studies that provided data on stroke risk at both 7 and 90 days. There is little evidence that the ABCD2 score picks out patients with established markers of high risk, such as carotid stenosis,supported by evidence that adding carotid stenosis to the ABCD2 or any other clinical prediction score see Chapter 5 improves recurrent stroke prediction.

For example, a young person with a history of IV drug use and a new murmur presenting with a brief episode of facial tingling might have an ABCD 2 score of 0 yet may be at high short-term risk of stroke. Patient will be seen in next available clinic. The power of the study with these 64 patients at the end agcd2 the study to statistically distinguish between the ABCD2 scores of patient with and without stroke was 0.

Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack. The ABCD2 score includes age, blood pressure elevation on first assessment after TIA, unilateral weakness, speech disturbance, duration of symptoms and diabetes mellitus as clinical variables, and predicted the early risk of stroke in the California and Oxford cohorts at 2, 7 and 90 days.

ABCD² score

Canadian Medical Association Journal. The ABCD2 score uses clinical features, medical history, and blood pressure to generate a number that can be used to determine the patient’s short-term risk of stroke.

Validation and refinement of scores to predict very early stroke risk after transient ischemic attack. Or create a new account it’s free. If TIA is diagnosed this period may be extended.


These risk factors were defined and chosen according to previous studies. Four studies provided some data on carotid stenosis by ABCD2 abcdd2. In a study of TIA patients who underwent brain imaging 3 or more days after the event, higher scores of California and ABCD rules which indicates higher short-term stroke risk were associated with positive DWI lesions [ 44 ].

Sanders Negative likelihood ratios ranged from sttroke. Two review authors MB, HM independently conducted data extraction and review the methodological quality of selected studies. It was initially validated in independent cohorts from those two locations but has now been validated in many other populations.

Also, normal distribution was assessed using normal quantile plot and histograms. In seven studies ,TIA patients were assessed within 24 hours of symptoms onset, in four studies within 48 hours, in one study within 72 hours, and in two studies within 7 days.

Can ABCD2 score predict the need for in-hospital intervention in patients with transient ischemic attacks? Annals of Internal Medicine. Similarly, adding imaging to the ABCD2 score [ 40 ] increased the area under the curve predictive accuracy from 0. Imaging information, such as whether an acute infarction is present, can also be very useful for prognostication and is not incorporated into the score. Can the ABCD risk score predict positive diagnostic testing for emergency department patients admitted for transient ischemic attack?

There is a variety of clinical and radiological methods for making that distinction and the ABCD2 scoring system is the easiest and most commonly used among these methods. ABCD2 and proportions of patients with tight carotid stenosis We examined all of the data on associations between the proportion of patients with high or low ABCD2 scores and an ipsilateral tight carotid stenosis, a key risk factor for recurrent stroke, to determine how many patients with tight carotid stenosis might have their investigations delayed and be at increased risk of stroke through having a low ABCD2 score.

Higher ABCD2 score predicts patients most likely to have true transient ischemic attack.

Moreover, diffusion-weighted imaging and clinical features have shown to be an independent predictors of short-term stroke risk independent of the ABCD scoring system. Current clinical guidelines 67 recommend urgent treatment only for patients with high ABCD2 scores, whereas patients with low scores should be triaged for further clinical assessment within 1 week.


Am J Emerg Med ; If the area is 0. Speech disturbance without weakness. In a prospective audit of 75 patients [ 59 ], 43 American Journal of Epidemiology.

Several studies have shown that positive DWI is associated with a short-term risk of abc2 at 90 days [ 4149 ]. Some independent validation studies of ABCD and ABCD2 scores have shown conflicting results in their discriminatory ability to predict stroke, 6970, and, in particular, a number of studies have suggested that high ABCD2 scores do not reliably identify patients with high stroke risk conditions, such as the presence of severe carotid stenosis.

Nine out of the 10 studies except Purroy et al. Formula Addition of the selected points. The number of recurrent events stroie 90 days was strangely low compared with that at 7 days see Table 5. The rules do not incorporate other variables known to also predict short-term risk of stroke such as Diffusion Weighted Imaging abnormalities DWI [ 13 ], large artery stenosis [ sfroke ], and atrial fibrillation [ 15 ]. The searches were initially run in Novemberand updated in November It is crucial to distinguish these patients in an ED.

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The ABCD and ABCD2 Scores and the Risk of Stroke following a TIA: A Narrative Review

A prospective study using the ABCD2 score in screening for minor stroke or transient ischaemic attack in referrals to a fast track clinic. In patients with syroke than one TIA in the past month, the duration of the longest event was used. The place of statistical methods in radiology and in the bigger picture Investigative Radiology.

Fax TIA referral form.